上皮细胞连接在维持机体正常生理功能和抵抗微生物入侵等方面起着重要的作用。本文就上皮细胞连接的方式、位置、结构、功能,上皮细胞连接相关蛋白表达异常与某些疾病间的关系,非口腔致病菌与上皮细胞连接间的关系,口腔致病菌与上皮细胞连接间的关系等研究进展作一综述。 Epithelial cell junctions play an important role in maintaining the normal physiological functions of the body and resisting microbial invasion. In this paper, the way of epithelial cell attachment, location, structure and function, the relationship between abnormal expression of epithelial cell junction protein and some diseases, the relationship between non-oral pathogenic bacteria and epithelial cells, the connection of oral pathogens and epithelial cells The relationship between the research progress is reviewed.