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慢性肝病患者糖代谢的异常在临床上越来越受到人们的重视,特别是肝硬化患者有较高糖耐量异常的发生率,本文主要是通过对肝硬化患者血浆胰岛素和血糖测定,探讨肝硬化患者糖代谢的异常改变。1 对象与方法1.1 研究对象 随机选择20例肝硬化失代偿期病人作为肝硬化组(其病因均为乙型病毒性肝炎),其中女8例,男12例,年龄25～72岁,病程5～10年。以正常健康人20例作为对照组,其中女12例,男8例,年龄24～55岁。1.2 研究方法 两组在试验前一日晚餐禁食,试验当日上午空腹及口服100g慢头或759葡萄糖2小时后分别采集静脉血测定血糖和胰岛素。以葡萄糖氧化酶法测定血糖,放射免疫测定法测定胰岛素(上海生物制品研究所放免药盒,空腹血浆胰岛素正常值
Abnormal glucose metabolism in patients with chronic liver disease in the clinical more and more people’s attention, especially in patients with liver cirrhosis have a higher incidence of impaired glucose tolerance, this paper is mainly through the plasma of patients with cirrhosis of insulin and blood glucose to explore patients with cirrhosis Abnormal changes in glucose metabolism. 1 Subjects and Methods 1.1 Subjects Randomly selected 20 patients with decompensated cirrhosis of the liver cirrhosis group (whose causes are hepatitis B virus), including 8 females, 12 males, aged 25 to 72 years, duration 5 to 10 years. Twenty normal healthy individuals were used as control group, including 12 females and 8 males, aged 24-55 years. 1.2 Methods Two groups of fasting dinner on the day before the test, the morning of the test fasting and oral administration of 100g or 759 glucose 2 hours after venous blood were collected for the determination of blood glucose and insulin. Glucose oxidase method for the determination of blood glucose, radioimmunoassay determination of insulin (Shanghai Institute of Biological Products RIA kit, fasting plasma insulin normal