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近十年来,肾脏和播散性念珠菌病的发病率明显增加,在这类患者中已分离鉴定出一种由蛋白质基质、念珠菌芽生孢子及假菌丝组成的念珠菌管型,但对其诊断价值及发病机理却 知之甚少。因此,作者用兔作为模型对其进行了研究。 方法和结果:选择雌性新西兰白兔52只,20只作为对照。32只静脉注射白念珠菌86-21b株芽生孢子10~5～10~8,其中8只用阿糖胞苷等处理以使之产生粒细胞缺乏,定时收集尿
In the recent ten years, the incidence of kidney and disseminated candidiasis has been significantly increased. Candida tube types consisting of protein matrix, budding conidia and pseudohyphae have been isolated and identified in these patients. However, Its diagnostic value and pathogenesis are poorly understood. Therefore, the author used rabbit as a model to study it. Methods and Results: Fifty-two female New Zealand white rabbits were selected and 20 were used as controls. 32 intravenous injection of Candida albicans 86-21b strains of spores 10 ~ 5 ~ 10 ~ 8, of which 8 were treated with cytarabine to produce agranulocytosis, regular urine collection