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枸橼酸克罗米芬(clomlphene citrate,CC)是诱导卵泡生长和促排卵药物,但在排卵率与妊娠成功数之间存在着差异。为研究CC对子宫内膜的影响,分析79例不育症患者在自然排卵周期(对照周期)及CC治疗周期(CC周期)的子宫内膜超声回声图像。经基础体温(BBT)测定、血清孕酮(P)水平及子宫内膜组织学检测证实:在对照周期中,患者均有自发排卵及正常黄体功能。每例于排卵前1~3天(增生晚期)及排卵后6~8天(分泌中期)行超声检查及用放免法(RIA)测定血清E_2。于排卵前2~4天,用
Clomiphene citrate (CC) is a drug that induces follicular growth and ovulation, but there is a difference between the ovulation rate and the number of successful pregnancies. In order to investigate the effect of CC on endometrium, endometrial ultrasound echo images of 79 cases of infertility were analyzed in the natural ovulation cycle (control cycle) and CC treatment cycle (CC cycle). The basal body temperature (BBT) determination, serum progesterone (P) levels and endometrial histological examination confirmed that: in the control cycle, patients have spontaneous ovulation and normal luteal function. In each case, serum E2 was measured by radioimmunoassay (RIA) 1 to 3 days before ovulation (late stage of hyperplasia) and 6 to 8 days after ovulation (middle stage of secretion). 2 to 4 days before ovulation, with