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正常灰鼠鼓膜紧张部的中央厚度为7～10μm,由外面的上皮层、中间层或固有层及内面的粘膜层组成,固有层为鼓膜最厚的部分,其主要成分为纤维层。本文应用电镜和光镜对26只成年灰鼠双侧中耳应用50%丙烯甘醇诱发胆脂瘤的鼓膜显微结构的变化进行了研究,丙烯甘醇是经鼓膜注入中耳的,注入药品后2～28日,在深麻醉下,行断头术进行颞骨的组织学观察,结果虽然鼓膜上皮层的破坏会立即出现,但其上皮的基底层仍旧保持完整,并为鼓膜上皮修复的再生基底。上皮修复的初期(应用丙烯甘醇后的4～7天)自上皮细胞伸出的伪足偶尔进入基底层,但这时上皮不会
The normal squirrel tympanic membrane tension central part of the thickness of 7 ~ 10μm, the outer layer of the epithelium, the middle layer or lamina propria and the inner mucosa layer, lamina propria is the thickest part of the tympanic membrane, the main component of the fibrous layer. In this paper, the changes of the tympanic membrane of cholesteatoma induced by 50% propylene glycol in middle ear of 26 adult squirrels were studied by electron microscope and light microscope. Propylene glycol was injected into the middle ear through the tympanic membrane, From February 28 to 28, under deep anesthesia, the decapitation technique was performed to observe the histology of the temporal bone. Although the destruction of the tympanic membrane epithelium immediately occurred, the basal layer of the epithelium remained intact and the regenerated base of the tympanic membrane epithelium was repaired . In the initial stage of epithelial repair (4 to 7 days after application of propylene glycol), the pseudopodia protruding from the epithelial cells occasionally enter the basal layer, but the epithelium does not