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目的:分析探讨头颈部恶性肿瘤(head and neck cancer, HNC)患者放射治疗(放疗)结束时的营养不良状况与营养相关症状和生活质量的关系。方法:通过便利抽样法选择2018年12月至2020年1月于北京某肿瘤医院放疗科门诊头颈组完成放疗的HNC患者为横断面研究对象。采用以下3种标准进行营养不良评定：体重指数(body mass index, BMI)80.0%的营养相关症状有疼痛、口干、唾液黏稠和味觉改变，对进食干扰程度>3分的营养相关症状有疼痛、吞咽困难、口腔溃疡、味觉改变和食欲不振；总体健康状况得分为(51.47±21.48)分。营养不良患者与营养正常患者相比，营养相关症状频率总分更高(40.09±9.23)分比(33.63±9.13)分，n P<0.01；对进食干扰程度总分更高(30.97±6.53)分比(25.85±6.54)分，n P<0.01；而总体健康状况得分则更低(48.10±20.59)分比(58.97±21.67)分，n P＝0.001。n 结论:HNC患者放疗结束时营养不良发生率高，营养相关症状普遍且对进食影响大，营养不良患者的营养相关症状更多、更重，生活质量更差，提示医护人员应持续关注放疗结束后HNC患者的营养状况和营养相关症状情况，进行营养干预及症状管理，以改善其生活质量。“,”Objective:To characterize the malnutrition status, nutrition impact symptoms and quality of life at the end of radiotherapy in patients with head and neck cancer (HNC) and explore the association between nutritional status with nutrition impact symptoms and quality of life.Methods:This was a cross-sectional study. HNC patients who completed radiotherapy in the head and neck radiotherapy department of a cancer hospital in Beijing from December 2018 to January 2020 were recruited through convenient sampling. Three criteria were used to assess malnutrition: (1)BMI 3 points were pain, dysphagia, mouth ulceration, taste alteration, and loss of appetite. The global health score of the patient was 51.47±21.48. Compared with patients with normal nutrition, patients with malnutrition had higher scores for NIS frequency (40.09±9.23 n vs 33.63±9.13, n P<0.01) and the interference with food intake (30.97±6.53n vs 25.85±6.54, n P<0.01), and lower global health scores (48.10±20.59n vs 58.97±21.67, n P=0.001).n Conclusions:At the end of radiotherapy, HNC patients had a high incidence of malnutrition. Nutrition impact symptoms were generally present and had a great influence on food intake. Patients with malnutrition experienced more and worse nutrition impact symptoms and worse quality of life. It is suggested that medical staff should continue to pay attention to the nutritional status and nutrition impact symptoms of HNC patients after radiotherapy and carry out nutritional intervention and symptom management to improve their quality of life.