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无钙灌流一定时间后复钙灌流的组织发生严重的功能和结构损伤的现象称之为钙反常(calcium paradox)。尽管这种现象存在一定的普遍性(在心肌、肾、骨骼肌、血管平滑肌中均存在),但迄今为止对肝脏在缺Ca~(2+)复Ca~(2+)过程中的变化及肝脏组织中Ca~(2+)和氧应激之间的关系还所知甚少。最近,Okuda等采用离体肝脏
After a period of calcium-free perfusion of calcium perfusion perfusion tissue serious functional and structural damage known as calcium anomalies (calcium paradox). Although this kind of phenomenon has certain universality (exists in myocardium, kidney, skeletal muscle and vascular smooth muscle), so far the changes of liver in Ca 2+ -free Ca 2+ process and The relationship between Ca 2+ and oxygen stress in liver tissue is also poorly understood. Recently, Okuda and others used isolated liver