骨质疏松是一种全身性的骨代谢疾病 ,以骨量减少、骨的微观结构退化 ,骨的脆性增加 ,且易于发生骨折为特征。许多对双胞胎或家庭进行的研究均证实 :遗传因素对骨密度变异的影响十分明显 ,约在特定年龄段的骨密度变异中占 50 %～ 85%。为进一步探讨骨质疏松的病因 ,进而研究其发 Osteoporosis is a systemic disease of bone metabolism characterized by a decrease in bone mass, degradation of the microstructure of the bone, increased fragility of the bone, and a tendency to fracture. Many studies of twins or families confirm that the effects of genetic factors on BMD variations are significant, accounting for about 50% to 85% of BMD variation at a particular age. To further explore the etiology of osteoporosis, and then study the hair