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进行性痘疹是一种用免疫方法预防天花的罕见并发症,但是它的发生却常与免疫缺乏性疾病或先前用免疫抑制剂治疗有关。作者报告1例进行性痘疹的病人,后来发展成为典型的类风湿性关节炎的过程。病者63岁,女性,1972年检查发现,在预防天花接种牛痘后出现反复发作性痘疹损害7个月。病者有哮喘反复发作史和手、膝轻微疼痛12个月的病史。体检发现,病人上臂、腿、背部呈现广泛的痘疹损害,全身性淋巴结病和肝脾肿大。此时没有关节炎的临床症状。类风湿性关节炎胶乳试验1∶64阳性,手和腕部X片显示关节联结处骨质疏松,掌指关节轻度
Progressive pox is a rare complication of immunization against smallpox, but its occurrence is often associated with immunodeficiency disease or previous treatment with immunosuppressive agents. The authors report a patient with progressive pox rash that later developed into a classic rheumatoid arthritis process. 63-year-old patient, female, examination in 1972 found that repeated vaccination in the prevention of smallpox inoculation varicella lesions 7 months. Patients with recurrent history of asthma and hand, knee slight pain for 12 months of history. Physical examination found that patients with upper arm, legs, back showed a wide range of pox lesions, systemic lymphadenopathy and hepatosplenomegaly. There are no clinical symptoms of arthritis at this time. Rheumatoid arthritis latex test 1:64 positive, hand and wrist X-ray showed osteoarthritis joints, metacarpophalangeal joint mild