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目的回顾性分析宁河区梅毒螺旋体抗体阳性检出率及分布特征。方法采用酶联免疫吸附试验(ELISA)、快速血浆反应素环状卡片试验(RPR)、梅毒螺旋体明胶颗粒凝集试验(TPPA)检测不同人群的梅毒阳性率。结果 2012-2016年宁河区梅毒抗体阳性检出率逐年减少,分别为5.88%、4.68%、3.91%、3.46%、2.31%,差异有统计学意义(P<0.05)。男性梅毒抗体阳性检出率为2.87%(114例),低于女性的6.87%(64例),差异有统计学意义(P<0.05)。2012-2016年梅毒抗体阳性检测者男女比逐年升高,分别为1.40∶1、1.70∶1、1.91∶1、1.88∶1、2.08∶1,差异有统计学意义(P<0.05)。吸毒人群、桑拿洗浴中心服务人员、男男同性恋(MSM)、外来务工人员、自愿咨询人员梅毒阳性率分别为2.29%、0.76%、0.31%、0.20%、0.08%,差异有统计学意义(P<0.05)。结论应进一步对宁河区高危人群、普通人群进行性病防治知识的宣传教育,加强综合监测和干预工作,控制梅毒流行,阻断母婴传播。
Objective To retrospectively analyze the positive detection rate and distribution characteristics of Treponema pallidum antibody in Ninghe district. Methods The positive rates of syphilis in different populations were detected by enzyme-linked immunosorbent assay (ELISA), rapid plasmaprorein cyclic card test (RPR) and Treponema pallidum gelatin particle agglutination test (TPPA). Results The positive rate of syphilis antibody in Ninghe district decreased from 2012 to 2016, accounting for 5.88%, 4.68%, 3.91%, 3.46% and 2.31% respectively. The difference was statistically significant (P <0.05). The detection rate of male syphilis was 2.87% (114 cases), lower than that of female (6.87%) (64 cases), the difference was statistically significant (P <0.05). The ratio of male to female in syphilis positive patients increased from year to year in 2012-2016, which were respectively 1.40:1,1.70:1,1.91:1,1.88:1,2.08:1, the difference was statistically significant (P <0.05). The positive rates of syphilis among drug users, sauna and bath center service providers, MSM, migrant workers and voluntary counselors were 2.29%, 0.76%, 0.31%, 0.20% and 0.08% respectively, with significant difference (P <0.05). Conclusions Publicity and education on STD prevention and control knowledge should be further carried out in high-risk and general population in Ninghe District. Intensive monitoring and intervention should be strengthened to control the prevalence of syphilis and block the mother-to-child transmission.