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观察了老龄雄性大鼠去势后骨骼重建的变化，并对其生物力学性能作了检测。结果老龄雄性大鼠去势4个月后，骨形成功能减退，而骨吸收仍然活跃，其松质骨和皮质骨骨量、生物力学性能均降低，且以松质骨改变更为明显，是男性骨质疏松症较理想的动物模型。
The changes of skeletal remodeling after the castration in aged male rats were observed and their biomechanical properties were examined. Results After 4 months of castration in aged male rats, the function of bone formation was diminished and the bone resorption was still active. The amount of cancellous bone and cortical bone and biomechanical properties were decreased, and the cancellous bone changed more obviously Male osteoporosis more ideal animal model.