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目的探讨血清γ-谷氨酰转移酶(GGT)与空腹血糖(FBG)的相关性。方法对江苏高邮地区人群分层随机抽样,纳入分析4248人,检测血清GGT、FBG及相关代谢指标;根据FBG水平分为A组2389人(FBG<5.6mmol/L)、B组1677人(5.6≤FBG≤6.9mmol/L)和C组182人(FBG≥7.0mmol/L)。结果 A、B、C三组GGT水平依次增高,男性高于女性(P<0.05)。多元逐步回归分析显示,GGT与FBG独立相关,女性较男性更显著。Logistic回归分析显示,第4四分位GGT水平与第1四分位相比,FBG升高(≥7.0mmol/L)的比值比(OR)(95%CI)值,男性为3.17(1.34,7.46),低于女性7.00(3.01,14.93)。结论 GGT是FBG升高的风险预测因子;女性FBG升高的风险高于相同GGT水平的男性。
Objective To investigate the relationship between serum G-glutamyl transferase (GGT) and fasting blood glucose (FBG). Methods The population of Gaoyou in Jiangsu Province was stratified randomly and 4248 were included in the analysis. Serum GGT, FBG and related metabolic parameters were detected. According to the level of FBG, there were 2389 people in group A (FBG <5.6mmol / L), 1677 persons in group B ≤ FBG ≤ 6.9 mmol / L) and Group C 182 (FBG ≥ 7.0 mmol / L). Results The levels of GGT in groups A, B and C were successively higher than those in males (P <0.05). Multivariate stepwise regression analysis showed that GGT was independently associated with FBG and that women were more prominent than men. Logistic regression analysis showed that the odds ratio (OR) (95% CI) of FBG increased (≥7.0 mmol / L) in the fourth quaternary compared with the first quaternary was 3.17 (1.34, 7.46 ), Below the female 7.00 (3.01, 14.93). Conclusions GGT is a risk predictor of FBG increase; women with higher FBG risk are higher than men with the same GGT level.