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目的:探讨老年非糖尿病原发性高血压患者尿微量白蛋白(MAU)与颈动脉硬化的相关性.方法:选取老年非糖尿病原发性高血压患者142例,根据24 h尿MAU量分为正常组78例(MAU＜30 mg/24 h)和MAU组64例(MAU 30～300 mg/24 h).比较两组患者颈动脉内膜中层厚度(CIMT)、CIMT增厚率以及颈动脉斑块发生率.结果:BMI、总胆固醇(CHOL)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、糖化血红蛋白(HbA1c)在MAU组中均高于正常组,差异具有统计学意义(均P＜0.05);CIMT、CIMT增厚率以及颈动脉斑块发生率在MAU组均高于正常组,差异具有统计学意义(均P＜0.05);MAU量与HbA1c(r=0.205,P=0.014)和CIMT值(r=0.294,P=0.000)呈正相关性.结论:老年非糖尿病高血压患者MAU与颈动脉硬化相关,可能是颈动脉硬化的危险因素.“,”Objective:To investigate the relationship between microalbuminuria and carotid atherosclerosis in the elderly hypertension patients without diabetes.Method:A total of 142 elderly patients with essential hypertension were involved and divided into normal group (n=78,microalbuminuria＜30 mg/24 h) and microalbuminuria group (n=64,microalbuminuria 30-300 mg/24 h).Carotid intima media thickness (CIMT),CIMT thicking rate and the incidence of plaque occurrence in the two groups were compared.Result:Compared with normal group,BMI,CHOL,TG,LDL-C and HbA1c increased in microalbuminuria group (all P＜0.05).Similarly,CI-MT,CIMT thicking rate and the incidence of plaque occurrence in the microalbuminuria group were also enhanced (all P＜0.05).Microalbuminuria was positively correlated with HbA1c (r =0.205,P =0.014) and CIMT (r =0.294,P=0.000).Conclusion:Microalbuminuria is related to the carotid atherosclerosis in the elderly hypertension patients without diabetes and maybe one of the risk factors of carotid atherosclerosis.