作者调查了全美医院用品联合公司的雇员,使用环氧乙烷(EO)作为气体消毒剂,工龄1～10年,采用临床检验和细胞学检验方法评价EO的危害。从1977～1980年的空气监测表明浓度为1～40ppm/每8hTWA,短时接触峰值<75ppm。结果与对照组临床检验无显著差异,细胞学检验两组有差异,包括稳定畸变和不稳定畸变数增高,总畸变细胞数增加,接触组中使用100％EO的 The authors investigated all US hospital supplies company employees, the use of ethylene oxide (EO) as a gas disinfectant, a length of 1 to 10 years, the use of clinical and cytological tests to assess the hazards of EO. Air monitoring from 1977 to 1980 showed a concentration of 1 to 40 ppm per 8 h of TWA with a short-term peak contact of <75 ppm. Results There was no significant difference between the two groups in the cytology test, including stable and unstable aberrations, and increased total number of cells with abnormality. In the contact group, 100% EO