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目的通过回顾分析围产期心肌病(PPCM)患者病例特点,为围产期心肌病的预防和治疗提供参考依据。方法入选围产期心肌病患者24例,记录并分析患者基本临床资料、检查结果、药物治疗方案及疾病转归。结果 24例患者平均年龄(28.21±5.38)岁,初次妊娠19例,产后2月内发病比例最高15例,腹泻或上呼吸道感染诱因4例,胸闷、心悸、水肿为最常见临床表现,合并贫血11例,高血压5例,脑利钠肽(BNP)(4 199.11±2 979.53)ng/L明显升高、左室射血分数(LVEF)(37.95±6.24)%明显减低,经治疗24例患者均好转。结论围产期加强预防意识,避免或减少病毒感染等可能的诱发因素,早期、及时和规范地治疗,围产期心肌病预后良好。
Objective To provide a reference for the prevention and treatment of perinatal cardiomyopathy by reviewing the characteristics of patients with perinatal cardiomyopathy (PPCM). Methods Twenty-four patients with perinatal cardiomyopathy were enrolled. Basic clinical data, test results, medication regimens and disease outcomes were recorded and analyzed. Results The average age of 24 patients (28.21 ± 5.38) years old, 19 cases of primary gestation, the highest incidence in 15 months postpartum in 15 cases, diarrhea or upper respiratory tract infection in 4 cases, chest tightness, palpitations, edema is the most common clinical manifestations, anemia 11 cases and 5 cases of hypertension. The BNP (4 199.11 ± 2 979.53) ng / L was significantly increased, and the left ventricular ejection fraction (LVEF) was significantly decreased (37.95 ± 6.24% Patients are better. Conclusions Perinatal period to enhance awareness of prevention, to avoid or reduce the possible triggers such as viral infection, early, timely and standardized treatment, perinatal cardiomyopathy prognosis is good.