病例报告 患儿,女,13岁。既往对青霉素、链霉素、磺胺、鲁米那及解热镇痛药有过敏史。1993年7月因上呼吸道感染口服双黄莲清热解毒口服液(哈白天鹅制药厂生产),每次20ml,每日2次。4天后患儿出现发热、胸闷、心慌、恶心、腹痛。查心率107次/min,头面部及四肢出现多形性红斑,皮疹为豆大至硬币大小的圆形或椭圆形斑疹,伴轻度水肿,中央色素较深呈紫红色,边缘为红色,境界清楚,呈对称性分布,四肢关节周围皮疹较密集,且各关节肿胀明显伴剧烈疼痛和强直,活动受限。四 Case report Children, female, 13 years old. Past history of penicillin, streptomycin, sulfonamides, luminal and antipyretic analgesics have a history of allergies. July 1993 due to upper respiratory tract infection Shuanghuanglian Qingrejiedu oral solution (Ha White Swan pharmaceutical production), each 20ml, 2 times a day. Four days later, the child developed fever, chest tightness, palpitation, nausea and abdominal pain. Check the heart rate 107 beats / min, the head and face and limbs appeared erythema multiforme, rash as beans to coin size round or oval rash, with mild edema, the central darker was purple fuchsia, the edge of the red, State clear, symmetrical distribution, rash around the limbs and joints more intensive, and the joint swelling with severe pain and stiffness, limited mobility. four