本文报道了自1985年5月至1990年12月我院应用吡哌酸片治疗急性菌痢560例,其中220例进行了系统的临床观察。吡哌酸成人0.5克,儿童30～50mg/kg/日 、一日3次;TMP成人0.1克,儿童5～10mg/kg/日,一日2次。结果220例经1个疗程(5～7天)治愈者203例(92.3％),二个疗程(7～14天)治愈者13例,4例无效,体温恢复正常平均1.1天, This article reports from May 1985 to December 1990 in our hospital application of piperacillin tablets in treatment of acute bacillary dysentery in 560 cases, of which 220 cases were systematically observed. Pipemidic acid 0.5g adult, children 30 ~ 50mg / kg / day, three times a day; TMP adult 0.1g, children 5 ~ 10mg / kg / day, 2 times a day. Results 203 cases (92.3%) were cured in 220 cases after one course of treatment (5-7 days). In two courses (7-14 days), 13 cases were cured, 4 cases were ineffective, and the body temperature returned to normal average 1.1 days.