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目的探讨妊娠和子宫肌瘤的相互作用,以及子宫肌瘤对分娩方式的影响。方法选择2010年1月-2015年12月台州市肿瘤医院收治的196例妊娠合并子宫肌瘤孕妇作为观察组,正常妊娠孕妇196例为对照组,观察子宫肌瘤对妊娠并发症及手术时间、术中出血量、住院天数等的影响,两组孕妇分娩方式情况和子宫肌瘤的变性情况。结果子宫浆膜下肌瘤、肌壁间肌瘤、黏膜下+混合性肌瘤妊娠并发症比较,差异有统计学意义(P<0.05);子宫肌瘤个数为1个、2~5个、≥6个妊娠并发症发生率比较,差异无统计学意义(P>0.05);子宫肌瘤直径≥5 cm孕妇妊娠并发症的发生率高于<5 cm孕妇(P>0.05);不同子宫肌瘤个数孕妇术中出血量比较,差异有统计学意义(P<0.05);子宫肌瘤直径≥5 cm孕妇术中出血量高于<5 cm孕妇(P<0.05);观察组剖宫产率明显高于对照组(P<0.05);129例行剖宫产+子宫肌瘤剔除术患者,术后子宫肌瘤病理结果显示肌瘤变性者63例,其中红色变性56例,变性率为43.4%。结论子宫肌瘤影响妊娠结局,孕期子宫肌瘤发生红色变性的比例高。
Objective To investigate the interaction between pregnancy and uterine fibroids and the effect of uterine fibroids on the mode of delivery. Methods 196 cases of pregnancy with uterine fibroids pregnant women admitted to Taizhou Cancer Hospital from January 2010 to December 2015 were selected as the observation group and 196 cases of normal pregnant women as the control group. The complications of uterine fibroids and the operation time, Intraoperative bleeding, the number of days of hospitalization, etc., the mode of delivery of two groups of pregnant women and the degeneration of uterine fibroids. Results There were significant differences in pregnancy complications between uterine subserosus fibroids, intramural fibroids and submucosa + mixed fibroids (P <0.05). The number of uterine leiomyomas was 1 and 2 to 5 (P> 0.05). The incidence of pregnancy complications in pregnant women with uterine fibroids ≥5 cm in diameter was significantly higher than that in <5 cm pregnant women (P> 0.05). There was no significant difference in the incidence of ≥6 gestational complications (P> 0.05) The number of fibroids bleeding in pregnant women, the difference was statistically significant (P <0.05); the diameter of uterine fibroids ≥ 5 cm bleeding in pregnant women was higher than <5 cm pregnant women (P <0.05); the observation group, the cesarean section (P <0.05). 129 patients underwent cesarean section and uterine myomectomy, postoperative pathological findings of fibroids showed fibroadenoma in 63 cases, of which 56 cases of red degeneration, the rate of degeneration 43.4%. Conclusion Uterine fibroids affect the outcome of pregnancy, pregnancy, uterine fibroids red degeneration high proportion.