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过去30多年里,对用高氟碳化物(perfluorocarbons)作为液体通气进行了广泛的研究。整体液体通气,即肺全部被高氟碳化物充填,使用一种装置产生高氟碳化物潮气量;部分液体通气,即肺部分地被高氟碳化物(约功能余气量大小)充填,用一般呼吸机进行通气。本前瞻性对照实验研究观察体重为12.7～25kg的绵羊在急性呼吸窘迫综合征(ARDS)情况下,肺顺应性和肺气体交换与气体通气比是否保持不变。于绵羊右心房注射0.07ml/kg油酸后再用生理盐水肺灌洗致肺损伤。两侧颈静脉用作体外生命支持,一侧肺动脉和一侧颈动脉予以
For more than 30 years, extensive research has been conducted on using liquid perfluorocarbons as a liquid aeration. The overall liquid ventilation, the lungs are all filled with high-fluoride carbides, the use of a device to produce a high amount of fluoride tidal volume; part of the liquid ventilation, the lungs are partially filled with high-fluoride carbides Ventilator ventilates. This prospective, controlled, experimental study investigated the compliance of lung compliance and whether the lung-gas exchange and the gas-to-air ratio remained unchanged in ARDS cases in sheep weighing 12.7-25 kg. In sheep right atrium after injection of 0.07ml / kg of oleic acid and then saline lung perfusion caused by lung injury. Both jugular veins serve as in vitro life support with one side of the pulmonary artery and one side of the carotid artery