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目的分析国内大骨节病病区儿童发硒含量及其影响因素,为制定合适的大骨节病防控措施提供依据。方法使用氢化物产生原子荧光光谱法(HG-AFS)测定儿童头发、大米和糌粑的含硒量,分析不同年龄、不同性别儿童的头发含硒特征及膳食结构对儿童硒营养状况的影响。利用SPSS14.0软件进行统计分析,P<0.05为差异有统计学意义。结果学龄前期(1～6岁)和学龄期(7～15岁)儿童头发的平均含硒量分别为(95.9±25.3)μg.kg-1(n=19)和(117.4±40.6)μg.kg-1(n=48),前者的发硒含量明显低于后者(t=-2.139,P=0.036)。对于学龄前期儿童,男童头发的含硒量略高于女童(t=0.253,P=0.803)。对于学龄期儿童,男童的发硒含量明显高于女童(t=2.560,P=0.014)。学校食堂的大米含硒量约为当地农户自制糌粑含硒量的2.5倍。结论膳食结构与儿童的硒营养状况直接相关,同时,适当的体育锻炼对改善大骨节病区儿童的硒营养状况也有一定的积极作用。
Objective To analyze the selenium content of children with Kashin-Beck disease in China and its influencing factors, and to provide the basis for making appropriate prevention and control measures of Kashin-Beck disease. Methods Hydrogenated atomic fluorescence spectrometry (HG-AFS) was used to determine the selenium content in hair, rice and slugs of children. The effects of dietary composition and selenium on the selenium nutrition of children were analyzed in different ages and sexes. Using SPSS14.0 software for statistical analysis, P <0.05 for the difference was statistically significant. Results The average selenium content in hair of preschool children (1-6 years old) and school age children (7-15 years old) were (95.9 ± 25.3) μg.kg-1 (n = 19) and (117.4 ± 40.6) μg, respectively. kg-1 (n = 48), the former hair selenium content was significantly lower than the latter (t = -2.139, P = 0.036). For preschool children, the selenium content of boys’ hair was slightly higher than that of girls (t = 0.253, P = 0.803). For school-age children, boys developed significantly higher levels of selenium than girls (t = 2.560, P = 0.014). School canteens selenium content of rice is about 2.5 times the amount of selenium contained in local farmers self-made 糌 粑. Conclusions The dietary structure is directly related to the status of selenium nutrition in children. At the same time, appropriate physical exercises have some positive effects on improving selenium nutritional status in children with KBD.