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目的:探讨阿卡波糖治疗2型糖尿病餐后低血糖的临床效果。方法:选取2015年03月至2016年9月我院接诊的2型糖尿病合并餐后低血糖患者122例,随机分为研究组与对照组,各61例。对照组患者给以盐酸二甲双胍缓释片口服治疗,研究组患者给以阿卡波糖治疗,共治疗4个疗程,比较两组治疗前及治疗后不同疗程时患者的FPG、2hPBG改善情况以及餐后低血糖发生情况。结果:治疗后第1周时两组患者的餐后低血糖发生差异无统计学意义(P>0.05);随着治疗的进展,研究组患者的餐后低血糖发生率明显的低于对照组,且研究组患者的FPG和2hPBG下降程度大于对照组,差异有统计学意义(P<0.05)。结论:对2型糖尿病餐后低血糖患者应用阿卡波糖进行治疗,可有效的改善患者的FPG和2hPBG水平,是一种有效的且安全的治疗方式。
Objective: To investigate the clinical effect of acarbose on postprandial hypoglycemia in type 2 diabetic patients. Methods: 122 cases of type 2 diabetes with postprandial hypoglycemia admitted from March 2015 to September 2016 in our hospital were randomly divided into study group and control group, each with 61 cases. Patients in the control group were treated with metformin hydrochloride sustained-release tablets orally, and patients in the study group were treated with acarbose for 4 cycles. The improvement of FPG and 2h PBG in both groups before and after treatment were compared After the occurrence of hypoglycemia. Results: There was no significant difference in postprandial hypoglycemia between the two groups at the first week after treatment (P> 0.05). With the progress of treatment, the incidence of postprandial hypoglycemia in the study group was significantly lower than that in the control group , And the reduction of FPG and 2hPBG in the study group was greater than that in the control group, the difference was statistically significant (P <0.05). Conclusion: The application of acarbose for postprandial hypoglycemia in type 2 diabetic patients can effectively improve FPG and 2hPBG levels in patients with post-prandial hypoglycemia, which is an effective and safe treatment.