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血液中含有多种蛋白成份,用现代免疫电泳可将其分成几十种,α_1酸性糖蛋白(α_1-Acidgl-ycoprotein.α_1AG)是其中之一,属于粘蛋白,1953年首先由Schmicl发现,分子量为45000,肝脏是合成α_1AG的主要器官。在手术、创伤、多种癌症、急性心肌梗塞等α_1AG升高,而重症肝病、肾病综合征等α_1AG降低。本文对52例原发肝癌(肝癌)与20例门脉性肝硬化(肝硬化)患者血清α_1AG进行了检测,以探求其临床意义,现将结果报道如下: 临床资料
Blood contains a variety of protein components, using modern immunoelectrophoresis can be divided into dozens of species, α_1 acid glycoprotein (α_1-Acidgl-ycoprotein.α_1AG) is one of them, belongs to mucin, first discovered by Schmicl in 1953, molecular weight 45000, the liver is the main organ for the synthesis of α_1AG. In surgery, trauma, a variety of cancer, acute myocardial infarction and other α_1AG increased, and severe liver disease, nephrotic syndrome and other lower α_1AG. In this paper, 52 cases of primary liver cancer (liver cancer) and 20 cases of portal cirrhosis (cirrhosis) in patients with serum α_1AG were detected in order to explore its clinical significance, the results reported are as follows: Clinical data