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目的：研究联用β七叶皂甙钠和复方丹参对急性脑梗塞患者脑血流量、血液流变学及血小板功能等的影响以取得更有效的治疗。方法：将６１例急性脑梗塞患者随机分成２组，比较联用β七叶皂甙钠和复方丹参（联合用药组）与用复方丹参治疗（复方丹参组）对患者脑血流量、血液流变学、血小板功能、超氧化物歧化酶的影响。结果：治疗２周后临床总有效率联合用药组为８４．６％，复方丹参组为５９．１％，２组比较有显著性差异（χ２＝４．９４，Ｐ＜０．０５）；联合用药组脑血流量、血液流变学、血小板功能、超氧化物歧化酶浓度治疗后均有明显改善（Ｐ＜０．０５～０．０１），而复方丹参组超氧化物歧化酶浓度提高（Ｐ＜０．０５），其它改善不明显。结论：联用β七叶皂甙钠和复方丹参可以改善脑梗塞患者脑血流量等，提高脑梗塞患者疗效。
Objective: To study the effects of β-aescinate and salvia miltiorrhiza on cerebral blood flow, hemorheology and platelet function in patients with acute cerebral infarction so as to obtain more effective treatment. Methods: Sixty-one patients with acute cerebral infarction were randomly divided into two groups. Compared with the combination of β-aescinate and salvia miltiorrhiza (combination group) and compound salvia miltiorrhiza (compound salvia miltiorrhiza group), the cerebral blood flow, hemorrheology , Platelet function, the effects of superoxide dismutase. Results: After 2 weeks of treatment, the total clinical effective rate was 84.6% in the combination group and 59.1% in the compound Salvia miltiorrhiza group. There was significant difference between the two groups (χ2 = 4.94, P <0.05) The blood flow, hemorheology, platelet function and superoxide dismutase (SOD) concentrations in treatment group were significantly improved (P <0.05 ~ 0.01), while the concentration of SOD in compound Salviae Miltiorrhizae increased P <0.05), other improvements are not obvious. Conclusion: Combination of β-aescinate and salvia miltiorrhiza can improve cerebral blood flow in patients with cerebral infarction and improve the curative effect in patients with cerebral infarction.