血管内皮细胞生长因子 (VEGF)是内皮细胞特异性的有丝分裂原 ,在许多生理和病理过程中 ,具有增加血管通透性、促进新生血管形成等生物学功能 ,与缺血性脑血管疾病的发生、发展关系密切。本文着重介绍脑缺血时VEGF及其受体表达、细胞来源和生物学作用 Vascular endothelial cell growth factor (VEGF) is an endothelial cell-specific mitogen with biological functions of increasing vascular permeability and promoting neovascularization in many physiological and pathological processes, and is associated with the occurrence of ischemic cerebrovascular diseases , Close development. This article focuses on the expression of VEGF and its receptor, the origin of cells and the biological role of cerebral ischemia