我科自1983年采用冷冻疗法治疗寻常疣,均于短期内获得满意效果。今将50例随访1年以上者报告如下:一、临床资料50例中,女17人,男33人。年龄5～70岁。皮损多发生于四肢,集中于手足伸侧,少数见于面、颈及胸部。病期2周至4年,多数患者治疗前曾外用剥脱剂或口服抗病毒药物,但无明显效果。二、治疗方法1.直接涂抹法凡皮损大于0.5cm 以上者采用直接涂抹法,即以消毒棉签浸蘸液氮,直接压迫于皮损处,每次压迫20～30秒钟。冻后在室温自然复温。每例每次反复3次冷冻融,最后涂以2%龙胆紫水溶液,然后无菌包扎。如局部皮损出现水疱,用消毒注射器抽出液体,涂龙胆紫水溶液,待自然结痂、脱落后,若疣基底仍未脱落,再行第二次冷冻。2.喷射法凡皮损小于0.5cm 者采用国产 Our department since 1983 using cryotherapy for the treatment of verruca vulgaris, are satisfied with the results in the short term. Now 50 cases were followed up for more than 1 year were reported as follows: First, the clinical data 50 cases, 17 females, 33 males. Age 5 to 70 years old. Skin lesions occur in the limbs, focus on the extensor side of hand and foot, a few found in the face, neck and chest. The duration of 2 weeks to 4 years, most patients before treatment with exfoliants or oral antiviral drugs, but no significant effect. Second, the treatment of 1 direct smear Where lesions greater than 0.5cm or more by direct smear method, that is disinfected cotton swab dipped in liquid nitrogen, directly oppression at the lesion at each compression of 20 to 30 seconds. After freezing at room temperature natural rewarming. Each case repeated 3 times each freeze thawing, and finally coated with 2% gentian violet solution, and then sterile dressing. If the local skin lesions appear blisters, with sterile syringes out of liquid, painted gentian violet solution until the natural scabs, off, if the wart substrate has not yet shed, and then a second frozen. 2. Spray method Where lesions less than 0.5cm made by domestic