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目的探讨不同时机宫体注射卡前列素氨丁三醇对预防高危产妇剖宫产产后出血的疗效。方法选择2014年1月-2015年4月在台州市立医院产科剖宫产分娩的有产后出血高危因素的94例产妇随机分为对照组和观察组各47例,两组在胎儿娩出后均予缩宫素20 U持续静脉滴注,在此基础上观察组在胎儿娩出后立即予宫体注射卡前列素氨丁三醇250μg,对照组在产后出血达到200 ml时再予宫体注射卡前列素氨丁三醇250μg,比较两组产妇术后出血量及产后出血发生率。结果观察组产妇产后24 h出血量(667.4±148.6)ml明显少于对照组的(834.4±183.8)ml,差异有统计学意义(P<0.01);产后出血发生率20.4%明显低于对照组的38.8%,差异有统计学意义(P<0.05)。结论对于合并产后出血高危因素的产妇,在剖宫产胎儿娩出后立即使用卡前列素氨丁三醇,较发现出血倾向后使用可减少产后出血发生率。
Objective To investigate the effect of intrauterine injection of carboprost trometamol on preventing bleeding after cesarean section in high-risk maternal women at different timings. Methods From January 2014 to April 2015, 94 pregnant women with high risk of postpartum hemorrhage who were delivered by cesarean section in Taizhou Municipal Hospital were randomly divided into control group and observation group, with 47 cases in each group. After delivery, both groups were given Oxytocin 20 U continuous intravenous infusion, on the basis of observation group immediately after the delivery of the fetus to the Palace of the body constant injection of carboprost trometamol 250μg, control group in the postpartum hemorrhage to 200 ml when the card body to the card before the injection Trimethoprim 250μg, postoperative bleeding and postpartum hemorrhage were compared between two groups. Results The amount of bleeding in the observation group was significantly lower than that in the control group (667.4 ± 148.6) ml at 24 hours postpartum (834.4 ± 183.8) ml, the difference was statistically significant (P <0.01). The incidence of postpartum hemorrhage was significantly lower than that in the control group Of the 38.8%, the difference was statistically significant (P <0.05). Conclusions For mothers with high risk of postpartum hemorrhage, the use of carboprost trometamol immediately after delivery of the cesarean section is more likely to result in a decrease in the incidence of postpartum hemorrhage.