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目的 :比较不同剂量的米索前列醇在足月妊娠引产中的效果。方法 :将 6 0例产妇分为 2 5 μg、5 0μg两组 ,均阴道置药 ,而后 4、8、12、2 4、48h给予宫颈评分 ,以及两组在用药总量、产程进展、母儿并发症方面进行比较。结果 :两组促宫颈成熟效果均好 ,且用药后 12～ 2 4h达高峰值。从引产至宫口开大 2cm ,以及宫口开大 2cm至开全的时间有差异 (P <0 0 5 ) ,两组用药总量有显著差异 (P <0 0 5 ) ,母儿并发症中宫缩过强、宫缩乏力均有显著差异 (P <0 0 5 )。结论 :使用 5 0 μg米索前列醇可引起宫缩过强 ,建议 2 5 μg阴道置药更安全、有效 ,接近自然产程。
OBJECTIVE: To compare the effects of different doses of misoprostol in term labor induced labor. Methods: 60 maternal women were divided into 2 groups of 25 μg and 50 μg. All patients were given vaginal drug, then cervical score was given at 4, 8, 12, 2, and 448 hours, and the total dosage, labor progress, Complications of complications were compared. Results: The two groups of cervical ripening effect are good, and 12 ~ 24h after treatment up to the peak. There was a significant difference between the two groups (P <0.05), maternal and child complications (P <0.05), the difference was significant Contractions in the palace too strong, uterine inertia were significantly different (P <0 05). Conclusion: The use of 50 μg of misoprostol can cause uterine contractions. It is recommended that 25 μg of vaginal drug be safe and effective, close to the natural process.