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目的:探讨四联抗Hp治疗消化性溃疡的临床疗效及耐药性。方法:收治Hp感染的消化性溃疡患者68例,随机分为两组。观察组给予四联抗Hp疗法,对照组给予三联抗Hp疗法,比较两组临床疗效。结果:观察组Hp根除率明显高于对照组,耐药性低于对照组,差异具有统计学意义(P<0.05)。观察组抗Hp治疗后溃疡面积、VAS评分明显低于对照组,差异具有统计学意义(P<0.05)。结论:四联抗Hp治疗消化性溃疡的疗效好,Hp根除率高。
Objective: To investigate the curative effect and drug resistance of peptic ulcer with quadruple anti-Hp treatment. Methods: 68 cases of peptic ulcer patients infected with Hp were randomly divided into two groups. The observation group received quadruple anti-Hp therapy, and the control group received triple anti-Hp therapy. The clinical efficacy was compared between the two groups. Results: The Hp eradication rate in the observation group was significantly higher than that in the control group, and the drug resistance was lower than that in the control group (P <0.05). The area of ulcer in the observation group after anti-Hp treatment was significantly lower than that in the control group (P <0.05). Conclusion: Quadruple anti-Hp treatment of peptic ulcer efficacy, Hp eradication rate.