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肿瘤的多药耐药性(multidrug resistance,MDR)是指肿瘤细胞对一种化疗药物产生耐药后,同时对未接触过的,结构和作用机制完全不同的化疗药物具有交叉耐药性。MDR具有两种表型:一种是首次使用化疗药物就产生耐药,称为原发性耐药(primary resistance);另一种则是在化疗过程中产生?
Tumor multidrug resistance (MDR) refers to tumor cells that are resistant to a chemotherapeutic drug and are also cross-resistant to untreated chemotherapeutic drugs that have a completely different structure and mechanism of action. MDR has two phenotypes: one is the first to use chemotherapy drug resistance, called primary resistance (primary resistance); the other is generated during chemotherapy?