肺淋巴瘤样肉芽肿病是一种罕见的肺部疾病,可累及多个器官。好发于免疫缺陷的患者,病因尚不十分清楚,目前多认为是与EB病毒感染相关的富含T细胞的B细胞淋巴瘤。临床表现为咳嗽、咳痰、胸痛及呼吸困难等;病理形态表现为显著的血管炎、多种炎细胞浸润及坏死。按EB病毒感染性不典型大细胞的数量多少组织学分为三级,不同分级对疾病的侵袭性、治疗与预后有所不同。本病结局是变化不定的,少数患者未经治疗即消退,但大多数患者预后不佳。 Pulmonary lymphoma-like granulomatosis is a rare lung disease that affects multiple organs. Occur in immunodeficiency patients, the etiology is not yet very clear, and currently considered to be associated with Epstein-Barr-virus-rich T cell-rich B cell lymphoma. Clinical manifestations of cough, sputum, chest pain and breathing difficulties; pathological manifestations of significant vasculitis, a variety of inflammatory cell infiltration and necrosis. By the number of atypical eosinophilic large cell EB virus histology is divided into three grades, different grading of the disease invasive, treatment and prognosis are different. The outcome of this disease is volatile, a small number of patients receded without treatment, but poor prognosis in most patients.