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目的探究加替沙星片溶出度测定条件。方法采用正交试验对该药的溶出度测定条件进行了筛选,采用紫外分光光度法测定吸光度,对转速、取样时间和溶出介质三个因素进行考察。结果和结论现行加替沙星片质量标准中溶出度的测定方法是科学合理的,
Objective To investigate the determination of dissolution of gatifloxacin tablets. Methods The orthogonal test was used to determine the dissolution conditions of the drug. The absorbance was measured by ultraviolet spectrophotometry. The factors of speed, sampling time and dissolution medium were investigated. Results and Conclusion The method of determination of dissolution in the current gatifloxacin tablets is scientific and reasonable.