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疱疹性咽峡炎是由柯萨奇病毒感染所致,我院自1992年以来.收治此病105例.应用干扰素与利巴韦林病毒唑对照,现报告如下:1 资料与方法1.1 一般资料1.1.1 病例 本院1992以来临床确诊为疱疹性咽峡炎住院患儿105例.用序贯方法随机分为两组.Ⅰ组(干扰素组):51例,男24例,女27例年龄3.5~12岁,平均8.87±1.36岁.Ⅱ组 利巴韦林(病毒唑组);54例,男28例,女26例,年龄2.5~12岁,平均 7.68±1.23岁.两组在年龄、性别上统计检验无显著性差异(P＞0.05).1.1.2 治愈标准 体温恢复正常.咽痛及疱疹消失,血象正象.1.2 治疗方法 Ⅰ组:干扰素5~10万,每日肌注1次;Ⅱ组:利巴韦林10~15mg/(kg.d)静滴或肌注,日1次,其余治疗两组相同.
Herpes angina is caused by Coxsackie virus infection in our hospital since 1992. The disease was treated 105 cases. The application of interferon and ribavirin ribavirin control, are reported as follows: 1 Materials and Methods 1.1 General Data 1.1.1 cases 105 cases of hospitalized patients with herpes angina since clinical diagnosis in our hospital in 1992. Randomized divided into two groups with sequential method.Ⅰ (interferon group): 51 cases, 24 males and 27 females Cases of age ranged from 3.5 to 12 years, with an average of 8.87 ± 1.36 years old.Group II ribavirin (ribavirin group); 54 cases, 28 males and 26 females, aged 2.5 to 12 years (average 7.68 ± 1.23 years old) There was no significant difference in age and sex between the two groups (P> 0.05) .1.1.2 Healing standard Body temperature returned to normal, sore throat and herpes disappeared, Day muscle injection 1; group II: ribavirin 10 ~ 15mg / (kg.d) intravenous infusion or intramuscular injection, day 1, the remaining treatment of the same two groups.