目的　探讨宫颈人乳头状瘤病毒 (HPV)感染的诊断及药物治疗的效果。方法　 12 8例宫颈涂片提示HPV感染 ,2 4 0例阴道镜下观察并作宫颈活检及PCR检测结果分析 ,三者均证实HPV感染者 2 4例 ,分组进行疣脱欣和聚甲酚磺醛药物治疗及随访。结果　两组患者临床治愈时间差异无显著性 (P >0 .0 5 )。结论　宫颈细胞学、阴道镜联合宫颈活检及PCR检测对宫颈亚临床型HPV感染的诊断具有重要意义。药物治疗具有无痛苦、无创面出血、感染等优点 ,易于患者接受。 Objective To investigate the diagnosis of cervical human papilloma virus (HPV) infection and the effect of drug treatment. Methods Twenty-eight cases of cervical smears suggested HPV infection, 240 cases were examined by colposcopy and analyzed by cervical biopsy and PCR. All three confirmed 24 cases of HPV infection, Aldehyde drug treatment and follow-up. Results There was no significant difference in clinical cure time between the two groups (P> 0.05). Conclusion Cervical cytology, colposcopy combined with cervical biopsy and PCR detection of cervical subclinical HPV infection is of great significance. Medical treatment with no pain, no bleeding, infection, etc., easy for patients to accept.