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目的了解广东省参与社区美沙酮维持治疗者人类免疫缺陷病毒(HIV)/获得性免疫缺陷综合征(AIDS)高危行为的影响因素。方法抽取广东省14家社区美沙酮门诊的7 288例受治者在治疗入组时的调查数据,采用logistic回归分析高危行为的影响因素。结果过去1个月注射吸毒者占80.24%,最近1次性行为使用安全套者占42.53%,HIV感染率为7.46%,丙型肝炎病毒(HCV)感染率为78.96%;多因素分析结果显示,HIV感染(OR=3.54)、HCV感染(OR=3.94)、吸毒年限长(OR=1.78)是受治者注射吸毒的危险因素,有工作(OR=0.85)及教育程度高(OR=0.83)是注射吸毒行为的保护因素;与家人关系良好(OR=1.41)、HIV感染(OR=1.44)、年龄高者(OR=2.63)在发生性行为时会倾向于使用安全套;而已婚有配偶(OR=0.76)倾向于进行无保护性行为。结论HIV感染、HCV感染和较长的吸毒年限是高危行为主要危险因素,与家人关系良好、高教育程度和有工作是其保护因素。
Objective To understand the influential factors of high risk behaviors of HIV / AIDS in community-based methadone maintenance treatment in Guangdong Province. Methods A total of 7 288 subjects from 14 community methadone clinics in Guangdong were enrolled in the survey. Logistic regression was used to analyze the influencing factors of high-risk behaviors. Results In the past 1 month, 80.24% of injecting drug users, 42.53% of condom users in the last sexual activity, 7.46% of HIV infections, and 78.96% of hepatitis C virus infection rates. Multivariate analysis showed that, HIV infection (OR = 3.54), HCV infection (OR = 3.94) and long drug abuse (OR = 1.78) were risk factors for injecting drug use in subjects with OR = 0.85 and education (OR = (OR = 1.41), HIV infection (OR = 1.44), and the older ones (OR = 2.63) tended to use condoms when they had sexual intercourse. The married couples OR = 0.76) tended to be unprotected. Conclusions HIV infection, HCV infection and longer drug-taking age are the main risk factors for high-risk behavior. Good relationship with family members, high educational level and having work are the protective factors.