用昆明种雄性小鼠同时诱发了低碘和高碘甲状腺肿、根据低、高碘甲状腺肿发生到形成过程中组织象的改变与血清甲状腺激素的水平,初步研究认为,高碘地方甲状腺肿的发病机理是,在高碘影影下,甲状腺仍能合成和释放足量的甲状腺激素,甲状腺肿大是由于胶质在滤泡腔中淤积,使滤泡腔扩大所致。也就是说,低碘和高碘甲状腺肿的发病机理不同各有自己的发生机制。 Low-iodine and high-iodine goiter were induced in male mice of Kunming at the same time. According to the changes of histological appearance and serum thyroid hormone during the formation of low and high iodine goiter, preliminary studies suggest that high iodine local goiter Pathogenesis is, in the high iodine shadow, the thyroid can still synthesize and release enough thyroid hormone, goiter is due to glial deposition in the follicular cavity, so that the expansion of the follicular cavity. In other words, low iodine and high iodine goiter different pathogenesis has its own mechanism.