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目的估算陕西省不同社会人口学特征的男男性行为者(MSM)2011年-2015年HIV新发感染率。方法陕西省5年监测MSM共4 609例纳入研究,HIV抗体确证阳性样本使用BED捕获酶联免疫法(BED)进行新发感染检测,按照社会人口学特征分层分析MSM新发感染率。结果 2011年-2015年陕西省MSM HIV新发感染率分别为5.00%、6.50%、4.52%、5.78%和4.49%。5年间HIV抗体阳性率和新发感染率差异无统计学意义(χ2值分别为7.389、0.031,P>0.05)。单因素分析显示,未婚的监测对象HIV新发感染率高于已婚及其他婚姻状态(OR=1.807),西安市的监测对象HIV新发感染率高于宝鸡市(OR=3.780)。多因素Logistic分析,地区是HIV抗体阳性(OR=2.900)和新发感染(OR=3.543)的影响因素(P<0.05),西安地区的MSM较宝鸡地区的MSM HIV抗体阳性和新发感染的危险性高。结论陕西省MSM HIV新发感染率较高,5年间疫情流行水平稳定,应针对低年龄段、高学历、未婚及西安市的MSM采取有效干预措施。
Objective To estimate the prevalence of HIV infection among MSM in different socio-demographic characteristics in Shaanxi Province from 2011 to 2015. Methods A total of 4 609 MSM surveillance MSM patients in Shaanxi Province were enrolled in this study. HIV positive antibody samples were detected by BED trap enzyme-linked immunosorbent assay (BED) for detection of new infections. Stratified MSM infection rates were analyzed according to socio-demographic characteristics. Results From 2011 to 2015, the rates of new HIV infection in MSM in Shaanxi Province were 5.00%, 6.50%, 4.52%, 5.78% and 4.49% respectively. There was no significant difference in HIV antibody positive rate and new infection rate in 5 years (χ2 = 7.389,0.031, P> 0.05). Univariate analysis showed that the rate of new HIV infection in unmarried subjects was higher than those in married and other marital status (OR = 1.807), and the rate of new HIV infection in monitoring subjects in Xi’an was higher than that in Baoji (OR = 3.780). Multivariate Logistic analysis showed that MSM in Xi’an was significantly higher than that in Baoji (MSM HIV positive and newly infected) in the areas of HIV positive (OR = 2.900) and new infections (OR = 3.543) High risk. Conclusions The prevalence of HIV infection in MSM in Shaanxi Province is high, and the epidemic prevalence is stable in five years. Effective interventions should be taken for MSM with low age, high education, unmarried and Xi’an.