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目的了解2011-2015年呼和浩特市健康人群麻疹抗体水平,评价含麻疹成分疫苗的接种工作质量,为制定消除麻疹策略提供科学依据。方法 2011-2015年每年抽取2~4个县区,每个县区抽取0~6岁、7~12岁、13~19岁、20~29岁、30~岁组5个年龄组的健康人群,每组随机抽取35人,5年共1 573人,应用酶联免疫吸附法检测麻疹IgG抗体。结果 2011-2015年共检测1 573人,其中麻疹IgG抗体阳性1 482人,阳性率94.2%。不同年份间麻疹IgG抗体、不同年龄组间麻疹IgG抗体阳性率差异均有统计学意义(P<0.05),不同地区间麻疹IgG抗体阳性率差异无统计学意义(P>0.05)。结论 2011-2015年呼和浩特市健康人群麻疹IgG抗体水平较高,已建立一定的免疫屏障。但由于30~岁组人群的麻疹抗体水平较低,建议对该年龄组人群开展强化免疫,青少年组开展查漏补种;同时继续加强麻疹监测,努力实现消除麻疹目标。
Objective To understand the level of measles antibody in healthy population in Hohhot from 2011 to 2015 and to evaluate the quality of measles vaccination with measles vaccine ingredient and provide a scientific basis for formulating measles elimination strategy. Methods From 2011 to 2015, 2 ~ 4 counties were selected each year, and healthy population of 5 age groups of 0 ~ 6, 7 ~ 12, 13 ~ 19, 20 ~ 29, 30 ~ , 35 patients in each group were randomly selected, a total of 1 573 people in 5 years, measles IgG antibody was detected by enzyme-linked immunosorbent assay. Results A total of 1 573 pregnant women were detected in 2011-2015, of which 1 482 were measles IgG positive, with a positive rate of 94.2%. The positive rates of measles IgG antibodies in different years were significantly different between different age groups (P <0.05). There was no significant difference in the positive rates of measles IgG between different regions (P> 0.05). Conclusion The levels of measles IgG antibodies in healthy population in Hohhot from 2011 to 2015 are high, and a certain immune barrier has been established. However, due to the low level of measles antibody in the population of 30 ~ age group, it is recommended to strengthen the immunization against this age group, and the young group should carry out leak detection and replantation. At the same time, we should continue to strengthen the monitoring of measles and strive to eliminate the measles target.