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支气管哮喘是气道对周围刺激反应性异常增高,引起支气管痉挛狭窄而致发作性通气障碍,可经药物或自行缓解,临床表现为呼气性呼吸困难。近年在发病机理、临床表现和治疗上都取得了进展,现综述如下: 一、支气管哮喘发生机理目前对本病发生机理尚未完全明了,多数人认为它与变态反应及体内环磷酸腺苷(cAMP)与环磷酸鸟苷(cGMP)比值有关。变态反应是出于可溶性过敏原作用于机体免疫系统,使浆细胞产生反应素IgE。当相同的过敏原再次进入人体,接触特异性致敏的肥
Bronchial asthma is the airway to the surrounding irritant reactivity abnormally increased, causing bronchial spasm and stenosis caused by episodic ventilatory disorders, can be relieved by drugs or self-esteem, clinical manifestations of exhaled breathlessness. In recent years, the pathogenesis, clinical manifestations and treatment have made progress, are summarized as follows: First, the mechanism of bronchial asthma The pathogenesis of this disease is not yet fully understood, most people think it and allergy and cAMP (cAMP ) And cyclic guanosine monophosphate (cGMP) ratio. Allergy is the role of soluble allergens in the body’s immune system, so that plasma cells produce reactive element IgE. When the same allergen re-enters the body, contact with specific sensitized fertilizers