一、概述卷须霉素(Capreomycin(CPM),别名缠霉素、卷霉素、缠绕霉素、卷曲霉素和抗结核霉素等,商品名称为Capascat及Ogosta,主要是对结核分枝杆菌的感染有效,临床使用其硫酸盐或盐酸盐。 CPM是一个碱性水溶性、具有环状多肽类结构的抗生素,含有4个极相近的组分,称为CPMIA、ⅠB、ⅡA和ⅡB,ⅠA和ⅠB的含量约80～90％,ⅡA和ⅡB的含量约20～10％,起治疗作用的是CPMIA和 I. Overview Capreomycin (CPM), alias captopril, streptomycin, entangamycin, capreomycin and anti-tuberculin, etc., under the trade name Capascat and Ogosta, mainly for the Mycobacterium tuberculosis Infection is effective and clinical use of its sulfate or hydrochloride CPM is an alkaline water-soluble antibiotic with a cyclic peptide structure containing four very similar components called CPMIA, IB, IIA and IIB, IA And Ⅰ B content of about 80 to 90%, Ⅱ A and Ⅱ B content of about 20 to 10%, the therapeutic effect is CPMIA and