1癌干细胞理论肿瘤是危害人类健康的一大顽症。在发生机理方面,影响力比较大的假说主要有:基因突变假说、非整倍体假说以及表遗传改变假说。这是因为肿瘤细胞中总是存在着基因突变、染色体结构和数目改变以及表遗传改变等。但是,不论哪种假说都不能完全解释有关肿瘤的所有现象。癌干细胞假说最早是在20世纪70-80年代提出的,该假说认为:肿瘤组织与正常组织一样,是由处于各种分化等 A cancer stem cell theory Tumor is a major chronic disease that endangers human health. In the mechanism of occurrence, the influential hypothesis mainly includes: gene mutation hypothesis, aneuploidy hypothesis and table genetic change hypothesis. This is because tumor cells always have mutations, changes in chromosome structure and number, and epigenetic alterations. However, neither hypothesis can fully explain all phenomena related to tumors. The cancer stem cell hypothesis was first put forward in the 1970s and 1980s, the hypothesis that: tumor tissue and normal tissue, is in a variety of differentiation