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本文测定了29例健康人,34例慢支肺气肿病人和30例支哮病人的弥散功能、血气和通气功能的改变。本文证实各组慢支肺气肿病人的DLco等降低,尤以血气异常组显著,即PaO_2降低者DLco等多降低,提示测定DLco等有助于判断慢支肺气肿病人的病情。本文还证实DLco等降低和PaO_2降低无明显相关,DLco等降低不是PaO_2降低的主要原因。本文慢支血气正常组45.5%的病例DLco等降低,提示在部分病例DLco等降低先于血气的改变,如果弥散量测定和血气等测验并用可提高异常检出率。此外,支哮及支哮肺气肿组的DLco等多正常,故测定弥散功能对慢阻肺中几种疾患的鉴别诊断有一定意义。
In this paper, 29 healthy subjects, 34 patients with chronic bronchitis and 30 patients with bronchial asthma were measured diffusion function, blood gas and ventilation changes. This study confirmed that patients with chronic bronchitis emphysema DLco decreased, especially in the group of abnormal blood gas, that is, decreased PaO 2 DLco and so reduce, suggesting that the determination of DLco, etc. can help determine the condition of patients with chronic bronchitis emphysema. This article also confirmed DLco reduction and other PaO2 decreased no significant correlation, DLco reduction is not the main reason PaO2 decreased. In this paper, 45.5% cases of chronic bronchitis blood group decreased DLco, etc., suggesting that DLco in some cases to reduce blood gas changes before the change, if the dispersion volume measurement and blood gas and other tests can increase the anomaly detection rate. In addition, bronchial and bronchial emphysema group DLco and so normal, so the determination of diffuse function of chronic obstructive pulmonary disease in the differential diagnosis of some significance.