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目的 :探讨慢性淋巴细胞性甲状腺炎 (CLT)的诊断 ,以及CLT合并其它甲状腺疾病的治疗方案选择。方法 :回顾性分析该院 1988～ 2 0 0 1年收治的 4 9例CLT的临床资料。结果 :术前诊断 11例 ,诊断率为 2 2 .4 %(11/ 4 9) ,其中经细针穿刺细胞学检查 (FNAC)诊断 10例 ,均予以甲状腺素片治疗 ,疗效满意。其余 38例分别误诊为其它甲状腺疾病而施行手术 ,其中合并甲亢 5例 ,合并结节性甲状腺肿 5例 ,合并甲状腺腺瘤 4例 ,合并甲状腺癌 3例 ;手术组中随访 2 7例 (71.1% ) ,6例发生甲低。结论 :全面的血清免疫学检查 ,结合FNAC检查可提高CLT的诊断率。该病以非手术冶疗为主 ,对合并其它病变者 ,应根据病理类型选择合理的治疗方案。
Objective: To investigate the diagnosis of chronic lymphocytic thyroiditis (CLT) and the treatment options of CLT combined with other thyroid diseases. Methods: The clinical data of 49 cases of CLT treated in our hospital from 1988 to 2001 were retrospectively analyzed. Results: 11 cases were diagnosed preoperatively, with a diagnostic rate of 22.4% (11/49). Among them, 10 cases were diagnosed by FNAC, all of which were treated with thyroxine tablets. The results were satisfactory. The remaining 38 cases were misdiagnosed as other thyroid diseases and underwent surgery, including 5 cases of hyperthyroidism, nodular goiter in 5 cases, 4 cases of thyroid adenoma with thyroid cancer in 3 cases; surgical group were followed up 27 cases (71.1 %), 6 cases of hypothyroidism occurred. Conclusion: Comprehensive serum immunological examination combined with FNAC can improve the diagnostic rate of CLT. The disease is mainly non-surgical treatment of patients with other lesions, should be based on the type of pathology to choose a reasonable treatment.