微小RNA(microRNA,miRNA)在宫颈癌的发生、侵袭、转移和复发等过程中扮演重要角色,与其预后密切相关。它能在组织、血清和血浆等标本中稳定存在,可通过调控靶基因从而促进宫颈癌细胞凋亡,并能改变宫颈癌细胞对药物和射线的敏感性,这使得mi RNA有望成为一种与宫颈癌诊疗密切相关的新型分子标志物。就miRNA在宫颈癌的早期分子诊断、治疗以及预后判断等方面的最新研究进展作一综述。 MicroRNAs (miRNAs) play an important role in the development, invasion, metastasis and recurrence of cervical cancer and are closely related to their prognosis. It can stably exist in specimens such as tissue, serum and plasma. It can promote the apoptosis of cervical cancer cells by regulating target genes and change the sensitivity of cervical cancer cells to drugs and radiation. This makes mi RNA expected to become a Cervical cancer clinics are closely related to the new molecular markers. The latest research progress of miRNA in early molecular diagnosis, treatment and prognosis of cervical cancer is reviewed.