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采用酶免疫测定(EIA)和蛋白印迹法检测云南省临沧和昆明地区海洛因依赖者353例血清标本的抗-HIV,用EIA法检测319例甲、乙、丙、丁4型肝炎病毒(HV)的感染指标。结果,全部标本均未检出抗-HIV。4种HV总感染率为78.11%,混合感染率为40.07%。抗-HAV-IgM、HBVM、抗-HCV、HDAg和/或抗-HD-IgM阳性率分别为1.57%、63.97%、51.85%和5.79%。HBV、HCV混合感染率为35.35%。4种HV感染率男性为72.73%,女性90.91%。静脉吸毒者HBV和HCV感染率均昆明地区显著高于临沧地区,汉族显著高于少数民族。这表明,吸毒人群中存在有4型HV感染、以HBV、HCV感染最为严重,其原因主要与吸毒、注射器未经消毒和共用注射器有密切关系。
Serum samples from 353 heroin addicts in Lincang and Kunming of Yunnan Province were tested for anti-HIV by enzyme immunoassay (EIA) and Western blotting, and 319 cases of hepatitis A, B, C and D were detected by EIA ) Of the infection indicators. As a result, no anti-HIV was detected in all specimens. The total infection rate of four kinds of HVs was 78.11%, and the mixed infection rate was 40.07%. The positive rates of anti-HAV-IgM, HBVM, anti-HCV, HDAg and / or anti-HD-IgM were 1.57%, 63.97%, 51.85% and 5.79%, respectively. The combined infection rate of HBV and HCV was 35.35%. The four kinds of HV infection rate were 72.73% in males and 90.91% in females. HBV and HCV infection rates of intravenous drug users were significantly higher in Kunming area than in Lincang area, Han nationality was significantly higher than that of ethnic minorities. This indicates that there are 4 types of HV infection among drug users, and HBV and HCV infection are the most serious. The reasons are mainly related to drug abuse, unspiked syringes and shared syringes.