论文部分内容阅读
目的:通过检测胰腺癌病人的静息能量消耗(REE),评估病人代谢变化的情况,探讨其与营养状态的关系。方法:用间接能量测定法检测34例诊断为胰腺癌的病人(试验组)和同期30例腹股沟疝病人(对照组)的REE。通过人体成分分析仪检测机体组成[体质指数(BMI)、肌肉重、去脂体重、脂肪重、细胞内液量(ICF)、细胞外液量(ECF)等],将REE与营养指标作相关性分析。结果:试验组病人的REE非常显著高于地对照组(P<0.01)。呼吸商(RQ)较对照组明显降低(P<0.01)。试验组病人的BMI、体重、肌肉群、去脂体重、脂肪、细胞内液量等与对照组比显著减少(P<0.05);细胞外液量较对照组显著增加(P<0.05)。胰腺癌病人的REE与肌肉重、去脂体重、细胞内液均有显著负相关性(P<0.05),与脂肪重无显著相关性(P>0.05)。胰腺癌各病人REE的变化并不相同,其中REE升高者为55.88%,REE正常者为29.41%,REE降低者为14.71%。结论:胰腺癌病人REE显著增加,营养状况显著低下。REE的升高与营养不良相关性。
OBJECTIVE: To assess the metabolic changes in patients by detecting resting energy expenditure (REE) in patients with pancreatic cancer and to explore their relationship with nutritional status. Methods: 34 patients with pancreatic cancer (experimental group) and 30 patients with inguinal hernia (control group) were enrolled in this study. The body composition index (BMI, muscle mass, lean body mass, fat weight, intracellular fluid volume (ICF), extracellular fluid volume (ECF), etc.) Sexual analysis. Results: The REE in the test group was significantly higher than that in the control group (P <0.01). Respiratory quotient (RQ) was significantly lower than the control group (P <0.01). Compared with the control group, BMI, body weight, muscle mass, lean body fat, fat and intracellular fluid in the experimental group were significantly decreased (P <0.05); extracellular fluid volume was significantly increased (P <0.05) compared with the control group. There was a significant negative correlation between REE and muscle mass, lean body weight and intracellular fluid in patients with pancreatic cancer (P <0.05), but no significant correlation with REE (P> 0.05). The changes of REE in patients with pancreatic cancer were different, including 55.88% of those with elevated REE, 29.41% of those with normal REE and 14.71% of those with decreased REE. Conclusion: The REE of pancreatic cancer patients increased significantly, and the nutritional status was significantly lower. Elevated REE correlates with malnutrition.