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为了解尿毒症及血液透析与血清微量元素的关系，用等离子体发射光谱仪检测１０例未透析尿毒症患者、１０例透析尿毒症患者、２５例健康对照者血清Ｆｅ、Ａｌ、Ｓｉ、Ｂ、Ｃａ、Ｍｇ、Ａｓ、Ｍｏ、Ｓｂ、Ｓｅ、Ｔｌ含量。结果：透析组与未透析组年龄、肾功能指标、Ｈｂ、ｍＢｐ、Ｃｈ、ＴＧ、ＨＤＬ、ＬＤＬ均无显著性差别；两组患者血清Ｂ、Ｓｉ均比正常显著升高，血清Ｆｅ均比正常显著下降；血清Ａｌ、Ｍｇ仅在透析组比正常显著升高；透析组与未透析组比较仅Ａｌ、Ｍｇ显著升高，其余元素无显著性差别；血清Ｂ、Ｓｉ均与ＢｕＮ显著正相关，与Ｈｂ显著负相关。提示透析可增加血清Ａｌ、Ｍｇ含量。Ｂ、Ｓｉ升高可能对肾脏有直接毒性。Ｂ可能与尿毒症神经系统损害有关。Ｓｉ可抑制透析铝痴呆症的发展。
In order to understand the relationship between uremia and hemodialysis and serum microelement, the plasma levels of Fe, Al, Si, B, Ca in 10 cases of uremic patients without dialysis, 10 cases of dialysis uremia and 25 cases of healthy controls were detected by plasma emission spectrometry , Mg, As, Mo, Sb, Se, Tl content. Results: There was no significant difference in age, renal function index, Hb, mBp, Ch, TG, HDL and LDL between dialysis group and non-dialysis group. Serum B and Si in both groups were significantly higher than those in normal group and serum Fe was higher than normal The levels of Al and Mg in serum were significantly increased only in the dialysis group compared with those in the normal dialysis group. Al and Mg in the dialysis group and the non-dialysis group were significantly higher than those in the non-dialysis group, while the other elements showed no significant difference. Serum B and Si were positively correlated with BuN, Significant negative correlation with Hb. Dialysis can increase serum Al, Mg content. B, Si may have direct toxicity to the kidneys. B may be related to uremia and nervous system damage. Si can inhibit the development of dialysis aluminum dementia.