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PGD_2的合成子(9)的合成是以2-甲基环戊1,3-二酮(1)为原料,经烯醇醚化、烯丙基化、酸去保护、羧基的锂铝氢还原、臭氧化、氧化、甲酰化获得。
Synthesis of PGD_2 (9) is synthesized from 2-methylcyclopentadienyl 1,3-dione (1) by etherification, allylation, acid deprotection and lithium-aluminum hydride reduction of carboxyl , Ozonation, oxidation, formylation obtained.