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目的 :观察中药熏洗辅助治疗0~Ⅰ级糖尿病足的临床疗效。方法 :将58例患者随机分为2组各29例,对照组给予控制血糖及并发症、改善微循环、营养神经等常规治疗;观察组在对照组治疗基础上结合中药熏洗治疗。对比分析2组临床疗效,及治疗前后血液流变学及血流动力学指标变化、神经传导速度、血小板聚集率等情况。结果:总有效率观察组为89.7%,对照组为65.5%,2组比较,差异有统计学意义(P<0.05)。治疗后2组患者血液流变学各项指标均较治疗前降低(P<0.01);观察组治疗后各项指标均明显低于对照组(P<0.01)。治疗后2组患者足背动脉血管内径和动脉血流量值均较治疗前升高(P<0.01),峰值流速和谱宽度降低(P<0.01);观察组上述指标改善优于对照组(P<0.01)。治疗后2组血小板聚集率均较治疗前明显降低(P<0.01);观察组血小板聚集率低于对照组(P<0.05)。治疗后2组患者运动神经传导速度、感觉神经传导速度均较治疗前明显加快(P<0.01);观察组各项指标也明显高于对照组(P<0.01)。结论:中药熏洗辅助治疗0~Ⅰ级糖尿病足,能明显改善患者的临床症状体征,且能改善机体血液循环及神经传导功能。
Objective: To observe the clinical efficacy of traditional Chinese medicine fumigation and adjuvant treatment of 0 ~ Ⅰ diabetic foot. Methods: 58 patients were randomly divided into two groups of 29 cases, the control group was given control of blood glucose and complications, improve microcirculation, nutritional nerves and other conventional treatment; the observation group in the control group combined with traditional Chinese medicine fumigation treatment. The clinical curative effect and the changes of hemorheology, hemodynamics index, nerve conduction velocity and platelet aggregation rate before and after treatment were compared and analyzed. Results: The total effective rate was 89.7% in the observation group and 65.5% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the indexes of hemorrheology in both groups were lower than those before treatment (P <0.01). The indexes in the observation group were significantly lower than those in the control group (P <0.01). After treatment, the diameter of dorsal artery and the value of arterial blood flow in both groups were significantly higher than those before treatment (P <0.01), and the peak velocity and spectral width were decreased (P <0.01). The above indexes in the observation group were better than those in the control group P <0.01). After treatment, the platelet aggregation rate in both groups was significantly lower than that before treatment (P <0.01). The platelet aggregation rate in the observation group was lower than that in the control group (P <0.05). After treatment, the motor nerve conduction velocity and sensory nerve conduction velocity were significantly increased in both groups (P <0.01). The indexes in the observation group were also significantly higher than those in the control group (P <0.01). Conclusion: TCM fumigation and washing adjuvant treatment of 0 ~ Ⅰ diabetic foot can significantly improve the patient’s clinical signs and symptoms, and can improve the body’s blood circulation and nerve conduction function.