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目的:了解中药不良反应(ADR)发生的情况和特点,以促进合理用药。方法:对我院2007年1月～2011年12月收集到的75例中药ADR报告,按患者年龄、性别、引起ADR的药品种类、给药途径、剂型、涉及器官/系统以及临床表现等进行统计、分析。结果:75例ADR涉及中药品种48种,口服给药51例(68.0%)较静脉给药23例(30.7%)引起的多,胶囊剂引起的ADR略多(30.7%)。ADR所涉及的器官/系统以消化系统损害最多,皮肤及其附件损害次之。结论:应加强中药ADR监测意识,促进安全合理用药。
Objective: To understand the occurrence and characteristics of adverse drug reaction (ADR) in traditional Chinese medicine to promote rational drug use. Methods: 75 cases of Chinese traditional medicine ADR collected in our hospital from January 2007 to December 2011 were analyzed according to patient’s age and sex, the type of drug causing ADR, route of administration, dosage form, organ / system involved, and clinical manifestations Statistical Analysis. Results: 75 cases of ADR involved 48 kinds of traditional Chinese medicines. 51 cases (68.0%) were given more drug than 23 cases (30.7%) by intravenous administration. The ADR caused by capsules was slightly more (30.7%). The organ / system involved in ADR is the most damaging to the digestive system, followed by the skin and its appendages. Conclusion: We should strengthen the awareness of traditional Chinese medicine ADR monitoring and promote safe and rational drug use.