体外培养的胃粘膜细胞为研究胃粘膜细胞的功能以及致病因子、药物、激素对细胞的损伤、保护和对细胞功能的调控提供了简单而优越的模型。国外学者对大鼠、狗、兔以及人胃粘膜细胞的分离、纯化和培养方法都有报道,并在此基础上进行了一系列深入的研究。国内尚无此项工作的报道,本实验的目的是建立一套人正常胃粘膜细胞原代培养的方法,并对 In vitro cultured gastric mucosal cells provide a simple and superior model for studying the function of gastric mucosal cells and the pathogenic factors, drugs, hormones on cell damage, protection and regulation of cell function. Foreign scholars on rat, dog, rabbit and human gastric mucosal cells separation, purification and culture methods have been reported, and on this basis, conducted a series of in-depth studies. There is no report of this work in our country. The purpose of this experiment is to establish a set of methods for the primary culture of human normal gastric mucosal cells.